Laddar...
Full Domain Closure of the Ligand-binding Core of the Ionotropic Glutamate Receptor iGluR5 Induced by the High Affinity Agonist Dysiherbaine and the Functional Antagonist 8,9-Dideoxyneodysiherbaine
The prevailing structural model for ligand activation of ionotropic glutamate receptors posits that agonist efficacy arises from the stability and magnitude of induced domain closure in the ligand-binding core structure. Here we describe an exception to the correlation between ligand efficacy and do...
Sparad:
| Huvudupphovsmän: | , , , , , , , , , , , |
|---|---|
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
American Society for Biochemistry and Molecular Biology
2009
|
| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2682870/ https://ncbi.nlm.nih.gov/pubmed/19297335 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M808547200 |
| Taggar: |
Lägg till en tagg
Inga taggar, Lägg till första taggen!
|