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Exploring kainate receptor pharmacology using molecular dynamics simulations
Ionotropic glutamate receptors (iGluRs) are enticing targets for pharmaceutical research; however, the search for selective ligands is a laborious experimental process. Here we introduce a purely computational procedure as an approach to evaluate ligand–iGluR pharmacology. The ligands are docked int...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2876335/ https://ncbi.nlm.nih.gov/pubmed/19737573 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2009.08.019 |
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