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Antinociceptive effects of MSVIII-19, a functional antagonist of the GluK1 kainate receptor

The ionotropic glutamate receptor subunit, GluK1 (GluR5), is expressed in many regions of nervous system related to sensory transmission. Recently, a selective ligand for the GluK1 receptor, MSVIII-19 (8,9-dideoxy-neodysiherbaine), was synthesized as a derivative of dysiherbaine, a toxin isolated fr...

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Bibliografiske detaljer
Main Authors: Qiu, Chang-Shen, Wyhe, Leanne Lash-Van, Sasaki, Makoto, Sakai, Ryuichi, Swanson, Geoffrey T., Gereau, Robert W.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3079003/
https://ncbi.nlm.nih.gov/pubmed/21324591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pain.2011.01.018
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