SOX2 Is an Oncogene Activated by Recurrent 3q26.3 Amplifications in Human Lung Squamous Cell Carcinomas

Squamous cell carcinoma (SCC) of the lung is a frequent and aggressive cancer type. Gene amplifications, a known activating mechanism of oncogenes, target the 3q26-qter region as one of the most frequently gained/amplified genomic sites in SCC of various types. Here, we used array comparative genomi...

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Detalhes bibliográficos
Main Authors: Hussenet, Thomas, Dali, Soraya, Exinger, Julien, Monga, Ben, Jost, Bernard, Dembelé, Doulaye, Martinet, Nadine, Thibault, Christelle, Huelsken, Joerg, Brambilla, Elisabeth, du Manoir, Stanislas
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2813300/
https://ncbi.nlm.nih.gov/pubmed/20126410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008960
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