Progressive 3q Amplification Consistently Targets SOX2 in Preinvasive Squamous Lung Cancer

Rationale: Amplification of distal 3q is the most common genomic aberration in squamous lung cancer (SQC). SQC develops in a multistage progression from normal bronchial epithelium through dysplasia to invasive disease. Identifying the key driver events in the early pathogenesis of SQC will facilita...

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Main Authors: McCaughan, Frank, Pole, Jessica C. M., Bankier, Alan T., Konfortov, Bernard A., Carroll, Bernadette, Falzon, Mary, Rabbitts, Terence H., George, P. Jeremy, Dear, Paul H., Rabbitts, Pamela H.
Format: Artigo
Sprog:Inglês
Udgivet: American Thoracic Society 2010
Fag:
F. Lung Cancer and Oncologic Disorders
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2902760/
https://ncbi.nlm.nih.gov/pubmed/20299530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201001-0005OC
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