Loading...
Could Sirt1-mediated epigenetic effects contribute to the longevity response to dietary restriction and be mimicked by other dietary interventions?
Dietary restriction (DR) increases lifespan in a range of evolutionarily distinct species. The polyphenol resveratrol may be a dietary mimetic of some effects of DR. The pivotal role of the mammalian histone deacetylase (HDAC) Sirt1, and its homologue in other organisms, in mediating the effects of...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Springer Netherlands
2009
|
| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2813047/ https://ncbi.nlm.nih.gov/pubmed/19568959 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-009-9104-5 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|