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Effects of Sirt1 on DNA methylation and expression of genes affected by dietary restriction

Changes in DNA methylation across the life course may contribute to the ageing process. We hypothesised that some effects of dietary restriction to extend lifespan and/or mitigate against features of ageing result from changes in DNA methylation, so we determined if genes that respond to dietary res...

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Détails bibliographiques
Auteurs principaux: Ions, Laura J, Wakeling, Luisa A, Bosomworth, Helen J, Hardyman, Joy EJ, Escolme, Suzanne M, Swan, Daniel C, Valentine, Ruth A, Mathers, John C, Ford, Dianne
Format: Artigo
Langue:Inglês
Publié: Springer Netherlands 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3776097/
https://ncbi.nlm.nih.gov/pubmed/23229445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-012-9485-8
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