Anti-Amyloid Effects of Small Molecule Aβ-Binding Agents in PS1/APP Mice

AIMS: One promising approach for treatment of Alzheimer’s disease (AD) is use of anti-amyloid therapies, based on the hypothesis that increases in amyloid-beta (Aβ) deposits in brain are a major cause of AD. Several groups have focused on Aβ immunotherapy with some success. Small molecules derivativ...

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Detalhes bibliográficos
Main Authors: Cohen, A.D., Ikonomovic, M.D., Abrahamson, E.E., Paljug, W.R., DeKosky, S.T., Lefterov, I.M., Koldamova, R.P., Shao, L., Debnath, M.L., Mason, N.S., Mathis, C.A., Klunk, W.E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812908/
https://ncbi.nlm.nih.gov/pubmed/20119496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/157018009789057526
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