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Early AD pathology in a [C-11]PiB-negative case: a PiB-amyloid imaging, biochemical, and immunohistochemical study

Amyloid-β (Aβ) deposits are detectable in the brain in vivo using positron emission tomography (PET) and [C-11]-labeled Pittsburgh Compound B ([C-11]PiB); however, the sensitivity of this technique is not well understood. In this study, we examined Aβ pathology in an individual who had clinical diag...

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Main Authors: Ikonomovic, Milos D., Abrahamson, Eric E., Price, Julie C., Hamilton, Ronald L., Mathis, Chester A., Paljug, William R., Debnath, Manik L., Cohen, Anne D., Mizukami, Katsuyoshi, DeKosky, Steven T., Lopez, Oscar L., Klunk, William E.
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3383058/
https://ncbi.nlm.nih.gov/pubmed/22271153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-012-0943-2
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