Post-mortem correlates of in vivo PiB-PET amyloid imaging in a typical case of Alzheimer's disease

The positron emission tomography (PET) radiotracer Pittsburgh Compound-B (PiB) binds with high affinity to β-pleated sheet aggregates of the amyloid-β (Aβ) peptide in vitro. The in vivo retention of PiB in brains of people with Alzheimer's disease shows a regional distribution that is very simi...

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Autori principali: Ikonomovic, Milos D., Klunk, William E., Abrahamson, Eric E., Mathis, Chester A., Price, Julie C., Tsopelas, Nicholas D., Lopresti, Brian J., Ziolko, Scott, Bi, Wenzhu, Paljug, William R., Debnath, Manik L., Hope, Caroline E., Isanski, Barbara A., Hamilton, Ronald L., DeKosky, Steven T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2008
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2408940/
https://ncbi.nlm.nih.gov/pubmed/18339640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awn016
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