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Characterization of a novel focal adhesion kinase inhibitor in human platelets
Focal adhesion kinase (FAK) is activated in human platelets downstream of integrins, e.g. α(IIb)β(3), and other adhesion receptors e.g. GPVI. Mice in which platelets lack FAK have been shown to exhibit extended bleeding times and their platelets have been shown to display decreased spreading on fibr...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Academic Press
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2812699/ https://ncbi.nlm.nih.gov/pubmed/19716803 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2009.08.132 |
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