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Focal adhesion kinase inhibitors are potent anti‐angiogenic agents
Focal adhesion kinase (FAK), a cytoplasmic tyrosine kinase and scaffold protein localized to focal adhesions, is uniquely positioned at the convergence point of integrin and receptor tyrosine kinase signal transduction pathways. FAK is overexpressed in many tumor cells, hence various inhibitors targ...
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| Publicado no: | Mol Oncol |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5528320/ https://ncbi.nlm.nih.gov/pubmed/22075057 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2011.10.004 |
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