Focal adhesion kinase inhibitors are potent anti‐angiogenic agents

Focal adhesion kinase (FAK), a cytoplasmic tyrosine kinase and scaffold protein localized to focal adhesions, is uniquely positioned at the convergence point of integrin and receptor tyrosine kinase signal transduction pathways. FAK is overexpressed in many tumor cells, hence various inhibitors targ...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mol Oncol
Egile Nagusiak: Cabrita, Miguel A., Jones, Laura M., Quizi, Jennifer L., Sabourin, Luc A., McKay, Bruce C., Addison, Christina L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2011
Gaiak:
Papers
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528320/
https://ncbi.nlm.nih.gov/pubmed/22075057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2011.10.004
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