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Characterization of a novel focal adhesion kinase inhibitor in human platelets

Focal adhesion kinase (FAK) is activated in human platelets downstream of integrins, e.g. α(IIb)β(3), and other adhesion receptors e.g. GPVI. Mice in which platelets lack FAK have been shown to exhibit extended bleeding times and their platelets have been shown to display decreased spreading on fibr...

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Hlavní autoři: Jones, Matthew L., Shawe-Taylor, Amelia J., Williams, Christopher M., Poole, Alastair W.
Médium: Artigo
Jazyk:Inglês
Vydáno: Academic Press 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812699/
https://ncbi.nlm.nih.gov/pubmed/19716803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2009.08.132
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