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Flavin-dependent thymidylate synthase: A novel pathway towards thymine
For several decades only one chemical pathway was known for the de novo biosynthesis of the essential DNA nucleotide, thymidylate. This reaction catalyzed by thyA or TYMS encoded thymidylate synthases is the last committed step in the biosynthesis of thymidylate and proceeds via the reductive methyl...
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| Main Authors: | , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2009
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2812616/ https://ncbi.nlm.nih.gov/pubmed/19643076 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2009.07.016 |
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