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Antigen-induced Erk1/2 activation regulates Ets-1-mediated sensitization of CD8+ T cells for IL-12 responses

The presence of IL-12 during antigen stimulation instructs naive CD8+ T cells for long-term effector responses, but their mechanisms of collaboration are not understood completely. Herein, we report that CD8+ T cells (OT-I T cells) stimulated with antigen for a longer duration show enhanced sensitiz...

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Detalhes bibliográficos
Main Authors: Li, Qingsheng, Eppolito, Cheryl, Odunsi, Kunle, Shrikant, Protul A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Society for Leukocyte Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812555/
https://ncbi.nlm.nih.gov/pubmed/19843578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0409221
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