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Mechanism of the eukaryotic chaperonin: protein folding in the chamber of secrets
Chaperonins are key components of the cellular chaperone machinery. These large, cylindrical complexes contain a central cavity that binds to unfolded polypeptides and sequesters them from the cellular environment. Substrate folding then occurs in this central cavity in an ATP-dependent manner. The...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2004
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2812437/ https://ncbi.nlm.nih.gov/pubmed/15519848 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcb.2004.09.015 |
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