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Leflunomide Inhibition of BK Virus Replication in Renal Tubular Epithelial Cells
The immunomodulatory drug leflunomide is frequently used for treating polyomavirus-associated nephropathy, yet its antiviral mechanism is unclear. We characterized the effects of the active leflunomide metabolite A771726 (LEF-A) on the polyomavirus BK (BKV) life cycle in human renal tubular epitheli...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology (ASM)
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2812362/ https://ncbi.nlm.nih.gov/pubmed/19955306 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01737-09 |
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