Impaired Vasoconstriction and Nitric Oxide-Mediated Relaxation in Pulmonary Arteries of Hypoxia- and Monocrotaline-Induced Pulmonary Hypertensive Rats

Pulmonary hypertension (PH) is a life-threatening disease with unclear vascular mechanisms. We tested whether PH involves abnormal pulmonary vasoconstriction and impaired vasodilation. Male Sprague-Dawley rats were exposed to hypoxia (9% O(2)) for 2 weeks or injected with single dose of monocrotalin...

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Detaylı Bibliyografya
Asıl Yazarlar: Mam, Virak, Tanbe, Alain F., Vitali, Sally H., Arons, Elena, Christou, Helen A., Khalil, Raouf A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The American Society for Pharmacology and Experimental Therapeutics 2010
Konular:
Cardiovascular
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812110/
https://ncbi.nlm.nih.gov/pubmed/19915069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.109.160119
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