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Endothelin-3-dependent pulmonary vasoconstriction in monocrotaline-induced pulmonary arterial hypertension

Blockade of the endothelin (ET) system is beneficial in pulmonary arterial hypertension (PAH). The contribution of ET-3 and its interactions with ET receptors have never been evaluated in the monocrotaline (MCT)-induced model of PAH. Vasoreactivity of pulmonary arteries was investigated; ET-3 locali...

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Autores principales: Sauvageau, Stéphanie, Thorin, Eric, Villeneuve, Louis, Dupuis, Jocelyn
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3700876/
https://ncbi.nlm.nih.gov/pubmed/18771698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.peptides.2008.08.003
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