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Change in pharmacological effect of endothelin receptor antagonists in rats with pulmonary hypertension: Role of ET(B)-receptor expression levels
BACKGROUND AND PURPOSE: The endothelin (ET) system is activated in pulmonary arterial hypertension (PAH). The therapeutic value of pharmacological blockade of ET receptors has been demonstrated in various animal models and led to the current approval and continued development of these drugs for the...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3693983/ https://ncbi.nlm.nih.gov/pubmed/19489130 |
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