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Endothelin receptor antagonist and airway dysfunction in pulmonary arterial hypertension
BACKGROUND: In idiopathic pulmonary arterial hypertension (IPAH), peripheral airway obstruction is frequent. This is partially attributed to the mediator dysbalance, particularly an excess of endothelin-1 (ET-1), to increased pulmonary vascular and airway tonus and to local inflammation. Bosentan (E...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2807428/ https://ncbi.nlm.nih.gov/pubmed/20042085 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-10-129 |
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