Evaluation of Pneumococcal Polysaccharide Immunoassays Using a 22F Adsorption Step with Serum Samples from Infants Vaccinated with Conjugate Vaccines

The history of the pneumococcal polysaccharide enzyme-linked immunosorbent assay (ELISA) is characterized by a continuous search for increased specificity. A third-generation ELISA that uses 22F polysaccharide inhibition has increased the specificity of the assay, particularly at low antibody concen...

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Главные авторы: Poolman, Jan T., Frasch, Carl E., Käyhty, Helena, Lestrate, Pascal, Madhi, Shabir A., Henckaerts, Isabelle
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology (ASM) 2010
Предметы:
Vaccine Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812097/
https://ncbi.nlm.nih.gov/pubmed/19889940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00289-09
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