Pneumococcal Haemophilus influenzae Protein D Conjugate Vaccine Induces Antibodies That Inhibit Glycerophosphodiester Phosphodiesterase Activity of Protein D

Haemophilus influenzae outer membrane protein D (PD) is a glycerophosphodiester phosphodiesterase (GlpQ) activity-possessing virulence factor and a promising vaccine antigen, providing 35.3% efficacy against acute otitis media caused by nontypeable H. influenzae (NTHI) when it was used as a carrier...

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Detalhes bibliográficos
Main Authors: Toropainen, Maija, Raitolehto, Anna, Henckaerts, Isabelle, Wauters, Dominique, Poolman, Jan, Lestrate, Pascal, Käyhty, Helena
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2546825/
https://ncbi.nlm.nih.gov/pubmed/18644877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00418-08
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