Prediction of Pneumococcal Conjugate Vaccine Effectiveness against Invasive Pneumococcal Disease Using Opsonophagocytic Activity and Antibody Concentrations Determined by Enzyme-Linked Immunosorbent Assay with 22F Adsorption

We compared the abilities of two serological readouts, antipolysaccharide IgG antibody concentrations and opsonophagocytic activity (OPA) titers, to predict the clinical effectiveness of the 7-valent pneumococcal conjugate vaccine (7vCRM) against invasive pneumococcal disease (IPD). We also assessed...

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Detalhes bibliográficos
Main Authors: Schuerman, L., Wysocki, J., Tejedor, J. C., Knuf, M., Kim, K.-H., Poolman, J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Vaccine Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3232694/
https://ncbi.nlm.nih.gov/pubmed/21994351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.05313-11
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