Structural insights into the YAP and TEAD complex

The Yes-associated protein (YAP) transcriptional coactivator is a key regulator of organ size and a candidate human oncogene inhibited by the Hippo tumor suppressor pathway. The TEAD family of transcription factors binds directly to and mediates YAP-induced gene expression. Here we report the three-...

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Dettagli Bibliografici
Autori principali: Li, Ze, Zhao, Bin, Wang, Ping, Chen, Fei, Dong, Zhenghong, Yang, Huirong, Guan, Kun-Liang, Xu, Yanhui
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2010
Soggetti:
Research Communication
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2811825/
https://ncbi.nlm.nih.gov/pubmed/20123905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1865810
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