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Crystallization and preliminary crystallographic analysis of nosiheptide-resistance methyltransferase from Streptomyces actuosus in complex with SAM

Nosiheptide-resistance methyltransferase (NSR) methylates 23S rRNA at the nucleotide adenosine 1067 in Escherichia coli and thus contributes to resistance against nosiheptide, a sulfur-containing peptide antibiotic. Here, the expression, purification and crystallization of NSR from Streptomyces actu...

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Detalhes bibliográficos
Main Authors: Yang, Huirong, Wang, Ping, Dong, Zhenghong, Li, Xueyuan, Gong, Rui, Yang, Ying, Li, Ze, Xu, Youwei, Xu, Yanhui
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2864697/
https://ncbi.nlm.nih.gov/pubmed/20445264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309110011395
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