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Crystallization and preliminary crystallographic analysis of a PHD domain of human JARID1B

Histone lysine methylation can be removed by proteins containing JmjC domains in a sequence- and methylation state-specific manner. JARID1B, a protein containing PHD and JmjC domains, is a histone demethylase specific for H3K4me2 and H3K4me3 which requires Fe(II) and α-ketoglutarate (α-KG) as cofact...

詳細記述

保存先:
書誌詳細
主要な著者: Guo, Xue, Xu, Youwei, Wang, Ping, Li, Ze, Xu, Yanhui, Yang, Huirong
フォーマット: Artigo
言語:Inglês
出版事項: International Union of Crystallography 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3151125/
https://ncbi.nlm.nih.gov/pubmed/21821892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309111021981
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