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Crystal structure of TAZ-TEAD complex reveals a distinct interaction mode from that of YAP-TEAD complex
The Hippo pathway is a tumor suppressor pathway that is implicated in the regulation of organ size. The pathway has three components: the upstream regulatory factors, the kinase core, and the downstream transcriptional machinery, which consists of YAP, TAZ (transcription co-activators) and TEAD (tra...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5435683/ https://ncbi.nlm.nih.gov/pubmed/28515457 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-02219-9 |
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