TEADs Mediate Nuclear Retention of TAZ to Promote Oncogenic Transformation

The transcriptional coactivators YAP and TAZ are downstream targets inhibited by the Hippo tumor suppressor pathway. The expression level of TAZ is recently shown to be elevated in invasive breast cancer cells and some primary breast cancers. TAZ is important for breast cancer cell migration, invasi...

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Autors principals: Chan, Siew Wee, Lim, Chun Jye, Loo, Li Shen, Chong, Yaan Fun, Huang, Caixia, Hong, Wanjin
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2009
Matèries:
Molecular Basis of Cell and Developmental Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2682883/
https://ncbi.nlm.nih.gov/pubmed/19324876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M901568200
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