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A combat with the YAP/TAZ-TEAD oncoproteins for cancer therapy

The transcriptional co-regulators YAP and TAZ pair primarily with the TEAD family of transcription factors to elicit a gene expression signature that plays a prominent role in cancer development, progression and metastasis. YAP and TAZ endow cells with various oncogenic traits such that they sustain...

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Detalhes bibliográficos
Publicado no:Theranostics
Main Authors: Pobbati, Ajaybabu V., Hong, Wanjin
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7069086/
https://ncbi.nlm.nih.gov/pubmed/32206112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.40889
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