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Induction of tissue inhibitor of matrix metalloproteinase-2 by cholesterol depletion leads to the conversion of proMMP-2 into active MMP-2 in human dermal fibroblasts

Cholesterol is one of major components of cell membrane and plays a role in vesicular trafficking and cellular signaling. We investigated the effects of cholesterol on matrix metalloproteinase-2 (MMP-2) activation in human dermal fibroblasts. We found that tissue inhibitor of matrix metalloproteinas...

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Bibliografische gegevens
Hoofdauteurs: Kim, Sangmin, Oh, Jang-Hee, Lee, Youngae, Lee, Jeongyoon, Cho, Kwang Hyun, Chung, Jin Ho
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Korean Society for Biochemistry and Molecular Biology 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2811819/
https://ncbi.nlm.nih.gov/pubmed/19887895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3858/emm.2010.42.1.004
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