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Assessment of SNP streak statistics using gene drop simulation with linkage disequilibrium
We describe methods and programs for simulating the genotypes of individuals in a pedigree at large numbers of linked loci when the alleles of the founders are under linkage disequilibrium. Both simulation and estimation of linkage disequilibrium models are shown shown to be feasible on a genome wid...
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| Hlavní autor: | |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2010
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2811755/ https://ncbi.nlm.nih.gov/pubmed/19582786 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.20440 |
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