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A method and program for estimating graphical models for linkage disequilibrium that scale linearly with the number of loci, and their application to gene drop simulation

Motivation: Efficient models for genetic linkage disequilibrium (LD) are needed to enable appropriate statistical analysis of the dense, genome-wide single nucleotide polymorphism assays currently available. Results: Estimation of graphical models for LD within a restricted class of decomposable mod...

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Detalles Bibliográficos
Autor Principal: Thomas, Alun
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2009
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2677740/
https://ncbi.nlm.nih.gov/pubmed/19289443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btp146
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