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Linkage Disequilibrium Patterns and tagSNP Transferability among European Populations

The pattern of linkage disequilibrium (LD) is critical for association studies, in which disease-causing variants are identified by allelic association with adjacent markers. The aim of this study is to compare the LD patterns in several distinct European populations. We analyzed four genomic region...

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Bibliografske podrobnosti
Main Authors: Mueller, Jakob C., Lõhmussaar, Elin, Mägi, Reedik, Remm, Maido, Bettecken, Thomas, Lichtner, Peter, Biskup, Saskia, Illig, Thomas, Pfeufer, Arne, Luedemann, Jan, Schreiber, Stefan, Pramstaller, Peter, Pichler, Irene, Romeo, Giovanni, Gaddi, Anthony, Testa, Alessandra, Wichmann, Heinz-Erich, Metspalu, Andres, Meitinger, Thomas
Format: Artigo
Jezik:Inglês
Izdano: The American Society of Human Genetics 2005
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Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1196391/
https://ncbi.nlm.nih.gov/pubmed/15637659
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