Development of a single tube 640-plex genotyping method for detection of nucleic acid variations on microarrays

Detection of DNA sequence variation is critical to biomedical applications, including disease genetic identification, diagnosis and treatment, drug discovery and forensic analysis. Here, we describe an arrayed primer extension-based genotyping method (APEX-2) that allows multiplex (640-plex) DNA amp...

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Detalhes bibliográficos
Main Authors: Krjutškov, Kaarel, Andreson, Reidar, Mägi, Reedik, Nikopensius, Tiit, Khrunin, Andrey, Mihailov, Evelin, Tammekivi, Veronika, Sork, Helena, Remm, Maido, Metspalu, Andres
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2008
Assuntos:
Methods Online
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2475630/
https://ncbi.nlm.nih.gov/pubmed/18539607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn357
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