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Development of a single tube 640-plex genotyping method for detection of nucleic acid variations on microarrays

Detection of DNA sequence variation is critical to biomedical applications, including disease genetic identification, diagnosis and treatment, drug discovery and forensic analysis. Here, we describe an arrayed primer extension-based genotyping method (APEX-2) that allows multiplex (640-plex) DNA amp...

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Bibliographische Detailangaben
Hauptverfasser: Krjutškov, Kaarel, Andreson, Reidar, Mägi, Reedik, Nikopensius, Tiit, Khrunin, Andrey, Mihailov, Evelin, Tammekivi, Veronika, Sork, Helena, Remm, Maido, Metspalu, Andres
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2475630/
https://ncbi.nlm.nih.gov/pubmed/18539607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn357
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