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Assessment of SNP streak statistics using gene drop simulation with linkage disequilibrium

We describe methods and programs for simulating the genotypes of individuals in a pedigree at large numbers of linked loci when the alleles of the founders are under linkage disequilibrium. Both simulation and estimation of linkage disequilibrium models are shown shown to be feasible on a genome wid...

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Autor principal: Thomas, Alun
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2811755/
https://ncbi.nlm.nih.gov/pubmed/19582786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.20440
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