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Activation of sphingosine 1-phosphate receptor-1 by FTY720 is neuroprotective after ischemic stroke in rats
BACKGROUND AND PURPOSE: FTY720 is a known sphingosine-1-phosphate (S1P) receptor agonist. In the present study we investigated the neuroprotective effect of postischemic administration of FTY720 in rats with 2 hours transient middle cerebral artery occlusion (MCAO). METHODS: One hundred eleven male...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2811754/ https://ncbi.nlm.nih.gov/pubmed/19940275 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.109.568899 |
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