The sphingosine 1-phosphate receptor agonist FTY720 is neuroprotective after cuprizone-induced CNS demyelination

BACKGROUND AND PURPOSE: Modulation of the sphingosine 1-phosphate receptor is an approved treatment for relapsing multiple sclerosis because of its anti-inflammatory effect of retaining lymphocytes within the lymph nodes. Here, we evaluated the potential of an agonist at this receptor, FTY720 (fingo...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Br J Pharmacol
Main Authors: Slowik, A, Schmidt, T, Beyer, C, Amor, S, Clarner, T, Kipp, M
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Publishing Ltd 2015
Teme:
Research Papers
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4280969/
https://ncbi.nlm.nih.gov/pubmed/25220526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12938
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