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Functional Antagonism of Sphingosine-1-Phosphate Receptor 1 Prevents Cuprizone-Induced Demyelination

Recent evidence suggests that the oral drug Fingolimod (FTY720) for relapsing-remitting multiple sclerosis (MS) may act directly on the central nervous system (CNS) and modulate disease pathogenesis and progression in experimental models of MS. However, the specific subtype of S1P receptors that med...

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Detalhes bibliográficos
Publicado no:Glia
Main Authors: Kim, SunJa, Bielawski, Jacek, Yang, Hyunmin, Kong, Yu, Zhou, Beiyan, Li, Jianrong
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5773114/
https://ncbi.nlm.nih.gov/pubmed/29193293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.23272
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