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Genetic deficiency of decorin causes intestinal tumor formation through disruption of intestinal cell maturation
Decorin is a member of the small leucine-rich proteoglycan gene family and plays an important role in suppressing cancer cell growth and metastasis. To elucidate the importance of decorin in intestinal carcinogenesis, a decorin-deficient (Dcn(−/−)) mouse model was employed. We found that targeted in...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2811538/ https://ncbi.nlm.nih.gov/pubmed/18550571 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgn141 |
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