Decorin-mediated inhibition of colorectal cancer growth and migration is associated with E-cadherin in vitro and in mice

Previous studies have shown that decorin expression is significantly reduced in colorectal cancer tissues and cancer cells, and genetic deletion of the decorin gene is sufficient to cause intestinal tumor formation in mice, resulting from a downregulation of p21, p27(kip1) and E-cadherin and an upre...

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Hlavní autoři: Bi, Xiuli, Pohl, Nicole M., Qian, Zhibin, Yang, George R., Gou, Yuan, Guzman, Grace, Kajdacsy-Balla, Andre, Iozzo, Renato V., Yang, Wancai
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2012
Témata:
Biology, Genetics and Epigenetics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3271272/
https://ncbi.nlm.nih.gov/pubmed/22159220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgr293
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