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Decorin-mediated inhibition of colorectal cancer growth and migration is associated with E-cadherin in vitro and in mice
Previous studies have shown that decorin expression is significantly reduced in colorectal cancer tissues and cancer cells, and genetic deletion of the decorin gene is sufficient to cause intestinal tumor formation in mice, resulting from a downregulation of p21, p27(kip1) and E-cadherin and an upre...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3271272/ https://ncbi.nlm.nih.gov/pubmed/22159220 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgr293 |
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