Genetic deficiency of decorin causes intestinal tumor formation through disruption of intestinal cell maturation

Decorin is a member of the small leucine-rich proteoglycan gene family and plays an important role in suppressing cancer cell growth and metastasis. To elucidate the importance of decorin in intestinal carcinogenesis, a decorin-deficient (Dcn(−/−)) mouse model was employed. We found that targeted in...

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Bibliografski detalji
Glavni autori: Bi, Xiuli, Tong, Chang, Dockendorff, Ashley, Bancroft, Laura, Gallagher, Lindsay, Guzman, Grace, Iozzo, Renato V., Augenlicht, Leonard H., Yang, Wancai
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2008
Teme:
Carcinogenesis
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2811538/
https://ncbi.nlm.nih.gov/pubmed/18550571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgn141
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