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A quantitative study of the recruitment potential of all intracellular tyrosine residues on EGFR, FGFR1 and IGF1R

Receptor tyrosine kinases transmit and process extracellular cues by recruiting intracellular signaling proteins to sites of tyrosine phosphorylation. Using protein microarrays comprising virtually every human SH2 and PTB domain, we generated quantitative protein interaction maps for three well-stud...

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Autors principals: Kaushansky, Alexis, Gordus, Andrew, Chang, Bryan, Rush, John, MacBeath, Gavin
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2811368/
https://ncbi.nlm.nih.gov/pubmed/18493663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/b801018h
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