טוען...

Linear combinations of docking affinities explain quantitative differences in RTK signaling

Receptor tyrosine kinases (RTKs) process extracellular cues by activating a broad array of signaling proteins. Paradoxically, they often use the same proteins to elicit diverse and even opposing phenotypic responses. Binary, ‘on–off' wiring diagrams are therefore inadequate to explain their dif...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Gordus, Andrew, Krall, Jordan A, Beyer, Elsa M, Kaushansky, Alexis, Wolf-Yadlin, Alejandro, Sevecka, Mark, Chang, Bryan H, Rush, John, MacBeath, Gavin
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Publishing Group 2009
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2644171/
https://ncbi.nlm.nih.gov/pubmed/19156127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2008.72
תגים: הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!