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Phosphotyrosine Signaling Proteins that Drive Oncogenesis Tend to be Highly Interconnected

Mutation and overexpression of receptor tyrosine kinases or the proteins they regulate serve as oncogenic drivers in diverse cancers. To better understand receptor tyrosine kinase signaling and its link to oncogenesis, we used protein microarrays to systematically and quantitatively measure interact...

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Библиографические подробности
Главные авторы: Koytiger, Grigoriy, Kaushansky, Alexis, Gordus, Andrew, Rush, John, Sorger, Peter K., MacBeath, Gavin
Формат: Artigo
Язык:Inglês
Опубликовано: The American Society for Biochemistry and Molecular Biology 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3650332/
https://ncbi.nlm.nih.gov/pubmed/23358503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M112.025858
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