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Tensin2 is a novel mediator in thrombopoietin (TPO)-induced cellular proliferation by promoting Akt signaling

Thrombopoietin (TPO) and its receptor c-Mpl are essential in the regulation of the hematopoietic stem and progenitors cells as well as for the differentiation of megakaryocytes into mature platelets. Once TPO binds to its receptor, an intracellular signaling process is initiated through Janus kinase...

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Hlavní autoři: Jung, Andre Scott, Kaushansky, Alexis, MacBeath, Gavin, Kaushansky, Kenneth
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3233486/
https://ncbi.nlm.nih.gov/pubmed/21527831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.10.11.15776
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