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Tensin2 is a novel mediator in thrombopoietin (TPO)-induced cellular proliferation by promoting Akt signaling

Thrombopoietin (TPO) and its receptor c-Mpl are essential in the regulation of the hematopoietic stem and progenitors cells as well as for the differentiation of megakaryocytes into mature platelets. Once TPO binds to its receptor, an intracellular signaling process is initiated through Janus kinase...

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Detalhes bibliográficos
Main Authors: Jung, Andre Scott, Kaushansky, Alexis, MacBeath, Gavin, Kaushansky, Kenneth
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3233486/
https://ncbi.nlm.nih.gov/pubmed/21527831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.10.11.15776
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