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GABA(A) receptor agonist mitigates homocysteine-induced cerebrovascular remodeling in knockout mice
Individuals with homozygous deficiency in cystathionine-β-synthase (CBS) develop high levels of homocysteine in plasma, a condition known as homocysteinuria. Mental retardation ensues with death in teens; the heterozygous live normally but develop vascular dementia and Alzheimer's disease (AD)...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2811264/ https://ncbi.nlm.nih.gov/pubmed/18547546 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2008.04.021 |
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