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γ-Aminbuturic Acid A Receptor Mitigates Homocysteine-Induced Endothelial Cell Permeability

Many cerebrovascular disorders are accompanied by an increased homocysteine (Hcy) levels. We have previously shown that acute hyperhomocysteinemia (HHcy) leads to an increased microvascular permeability in the mouse brain. Hcy competitively binds to γ -aminbuturic acid (GABA) receptors and may incre...

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Detalhes bibliográficos
Main Authors: Tyagi, Neetu, Moshal, Karni S., Tyagi, Suresh C., Lominadze, David
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819032/
https://ncbi.nlm.nih.gov/pubmed/18080868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10623320701746164
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